Chaetostoma joropo is a species of catfish in the family Loricariidae.

It is native to South America, where it occurs in the Cusiana River basin in the Orinoco drainage in Colombia.

[1] The species reaches at least 12.47 cm (4.9 inches) SL and was described in 2016 by Gustavo A. Ballen of the University of London, as well as Alexander Urbano-Bonilla and Javier A. Maldonado-Ocampo of the Pontifical Xavierian University.

[2] It appears in the aquarium trade, where it is frequently referred to by its L-number, which is L-445.

This species has reportedly been known to aquarists for quite some time prior to its 2016 scientific description.