Chalepensin is a chemical compound of the furanocoumarin class.

[3] Chalepensin forms colorless crystalline needles with a melting point of 82-83 °C.

[4] Chalepensin has been shown to have antifertility effects in female rats.

[5] This antifertility effect may provide some scientific evidence in support of the traditional uses of fringed rue[6] and modern use of rue oil (oil from plants of the genus Ruta) in South America[7] as an abortifacient.

Chalepensis has also been shown to have antibacterial activity against Streptococcus mutans and methicillin-resistant Staphylococcus aureus (MRSA).