[1][2] Chalermchai Sri-on was born on 7 March 1965 in Pran Buri District, Prachuap Khiri Khan Province.

[4] Chalermchai started his political careers as a member of the Prachuap Khiri Khan Provincial Council in 1990 - 2000 and as the Chairman of the Prachuap Khiri Khan Provincial Council in 1995 to 1997 and was the first member of the Prachuap Khiri Khan Provincial House of Representatives in 2001 election and subsequent elections in 2005, 2007 and 2011.

Chalermchai is the Deputy Leader of the Democrat Party responsible of the central region.

Subsequently, in the Cabinet reshuffle of the government of Abhisit Vejjajiva on 6 June 2010, he was appointed Minister of Labor.

In the government of Prayut Chan-o-cha, he was appointed Minister of Agriculture and Cooperatives.