She was revealed to the public when participating in the TV Show La Classe in 1987.
On the radio, she is a recurring member of the daily comedy programme Les Grosses Têtes, hosted by Laurent Ruquier.
Since 2016, she also has had more important on-screen roles, especially due to the success of the movie We Are Family (2016) and its two sequels : C'est quoi cette mamie ?!
She also frequently works with the younger generation of directors like Philippe Lacheau and Tarek Boudali.
Ladesou met her husband Michel Ansault and with whom she had three children, two boys, Alix (who died in a car accident), Julien and a daughter, the actress Clémence Ansault.