Frederick and Ramona Foxen Wickenden purchased the property where the chapel sits from the federal government in 1872.

In 1879, the chapel was dedicated by Francisco Mora y Borrell in behalf of Saint Ramon.

In 1972, the San Ramon Preservation group was formed to help protect the property from additional vandalism.

[2] In January, 1975, the chapel was named to the California Historical Landmarks list.

The San Ramon Chapel Preservation Committee (SRCPC), the organizing body that maintains the property and building, became a non-profit in 1976.

The next year, SRCPC offered to turn the property over to the Roman Catholic Archdiocese of Los Angeles.