It is named after Gutierre de Vargas Carvajal, Bishop of Plasencia, who is buried there.

When the saint's body was discovered in the late 13th century, two centuries after his death, King Alfonso XI ordered the construction in San Andres of an ark to hold his remains and a chapel in which to venerate his memory.

In the 18th century, San Isidro's remains were relocated to the Basílica de Nuestra Señora del Buen Consejo.

[1] It was given a heritage listing in 1931 and is protected as a Bien de Interés Cultural.

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