Chaplygin Street (Russian: Улица Чаплыгина) is a street in Zheleznodorozhny and Tsentralny districts of Novosibirsk, Russia.

The street consists of two fragments.

The first street fragment starts from the Street of Revolution, crosses Uritsky, Sovetskaya streets and forms a T-intersection with Krasny Avenue.

The second fragment starts from Serebrennikovskaya Street crosses Kamenskaya Street and ends in a city block.

Until 1920 the street was named the Asinkritovskaya, in honor of Asinkrit Lomachevsky, Governor of the Tomsk Governorate, later it was called the Rabochaya Street, and afterwards, the street was named in honor of Sergey Chaplygin.