She played the female lead in the 1962 film adaptation of Jose Rizal's El filibusterismo, directed by Gerardo de Leon.

Among her many films she also appeared in Eddie Romero's Manila, Open City (1967), Araw-Araw, Gabi-Gabi (1975) and Agila (1980); in Mike de Leon's Kisapmata (1981) and Batch '81 (1982); in Ishmael Bernal's Manila by Night (1980) and Hinugot sa Langit (1985); in Lino Brocka's Init (1979) and Ina, Kapatid, Anak (1979);[2] and as the narrator in Marilou Diaz-Abaya's Karnal (1983).

Other notable performances of Solís were featured in Angustia (1963), Tatlong Mukha ni Pandora (1963), Magda Sales (1964), Claudia (1966) and Boomerang (1966).

[3] She appeared in another Japanese film, The Princess and I, produced by Daiei Japan which had its Philippine premiere at the Lyric Theater in Escolta on October 10, 1962.

In the late 1980s, Solís won the chance to showcase her comedic skills, as well as to gain a younger set of fans, when she was cast opposite Vic Sotto, Alice Dixson and Aiza Seguerra in the sitcom Okay Ka, Fairy Ko!.

She played the imperious Ina Magenta, Enteng Kabisote's mother-in-law, a character which was loosely modeled after Agnes Moorehead's Endora on Bewitched.

Her performance in 1967's Dahil sa Isang Bulaklak, directed by Luis Nepomuceno, won her Best Actress award at the 1967 Asian Film Festival.