Messina's play, Homeland, which premiered in 2008, starred Sopranos actors Dan Grimaldi, Jason Cerbone, Joe Lisi, as well as Amir Darvish.
In May 2010, Messina directed and co-wrote (along with Vincent Gogliormella) the script Twas The Night Before a Brooklyn Christmas, starring Mario Cantone, Michael Rispoli and Robert Cuccioli, also at 45 Bleecker Street.
[8] Twilight Theatre Productions performed three of Messina's plays - Thompson Street, Lilac, and Fugazy - from June 21 through August 2, 2013, at Kenlake State Resort Park in Hardin, KY.[9] On September 22, 2013, The Abingdon Theatre hosted a special reading of three of Messina's plays: Fairies, Thompson Street, and Sinkhole, as part of a fundraiser for the theater.
The cast included (in alphabetical order): Michael Barbieri, Anthony DeSando, Alfredo Diaz, Nick Fondulis, Khalid Gonçalves, Steven LaChioma, Tom Alan Robbins, Scott Seidman, and Johnny Tammaro.
The plays, titled A Mooney for the Misbegotten, Fifteen Minutes of Shame, and Chubby & Glen, featured actors Jason Cerbone, Anthony DeSando, Mary Dimino, Nick Fondulis, Valerie Smaldone, Johnny Tammaro, and Michael Townsend Wright.
[13] The Abingdon Theatre Company presented a reading of Messina's play A ROOM OF MY OWN, starring Mario Cantone, Ralph Macchio, Joli Tribuzio, Tammaro, Barbieri, Jain, Antoinette LaVecchia and Michael Townsend Wright on April 21, 2015.
The autobiographical play is a bawdy, family comedy revolving around a writer telling the story of his life, as events and characters start to slowly slip away from his control.
[16] On November 13, 2012, a second reading of the play was done at 45 Bleecker Street, starring Cantone, Rachel Dratch, Zach Galligan, and Mike Barbieri, as well as Tammaro, and Jain.
[17] The Abingdon Theatre Company presented a reading of Charles Messina's play A Room of My Own, starring Cantone, Macchio, Joli Tribuzio, Tammaro, Barbieri, Jain, Antoinette LaVecchia and Michael Townsend Wright on April 21, 2015.
[19] The autobiographical play is a bawdy, family comedy revolving around a writer telling the story of his life, as events and characters start to slowly slip away from his control.
"[23] On March 18, 2019, BroadwayWorld announced that The Wanderer would begin a run at New Jersey's Paper Mill Playhouse in the spring of 2020, before its eventual Broadway debut.