Charles Nelson Manning (born March 31, 1979) is a former professional baseball relief pitcher who last played for the Southern Maryland Blue Crabs.

Manning was selected in the 9th round of the 2001 Major League Baseball Draft by the New York Yankees.

On July 31, 2003, Manning was traded to the Cincinnati Reds with Brandon Claussen for Aaron Boone.

Manning became a minor league free agent after the 2007 season and signed with the Washington Nationals.

He became a free agent again after the season, and did not pitch again until joining the Southern Maryland Blue Crabs in the Atlantic League of Professional Baseball in 2011, who he played with from 2011 to 2013.