Charles Edwin Smith (April 20, 1880 – January 3, 1929) was a pitcher in Major League Baseball who played from 1902 through 1914 for the Cleveland Bronchos (1902), Washington Senators (1906–1909), Boston Red Sox (1909–1911) and Chicago Cubs (1911–1914).

Smith always was a bad-luck pitcher[citation needed] either due to injury or playing on a bad baseball team.

He had a promising debut for Cleveland on August 6, 1902, defeating future Hall of Famer Rube Waddell and the Philadelphia Athletics, 5–4, at League Park.

Then, working with two days' rest, he shut out the Baltimore Orioles, 7–0, ending his rookie season with a 2–1 record in three starts.

In a 10-year career, Smith posted a 66–87 record with a 2.81 ERA in 212 appearances, including 148 starts, 87 complete games, 10 shutouts, three saves, and 1349+1⁄3 innings of work.