It was the first hospital in Charlottetown and was established in the former Bishop's Residence on the site of the present-day St. Dunstan's Basilica at the corner of Dorchester and Great George streets.

The Diocese of Charlottetown was involved in one final health care project in Prince Edward Island when it opened the Western Hospital in Alberton in 1944, also under the administration of the Sisters of St. Martha.

[1] The building on Haviland Street remained standing into the mid-1990s as it was re-purposed for provincial government offices, including motor vehicle licensing and driver testing under the Department of Transportation and Public Works.

As part of the expansion of the new Holland College facility, the former Charlottetown Hospital building was demolished to make room for a parking lot.

It was closed by the Sisters of St. Martha of Prince Edward Island and was subsequently sold to a private developer and renovated into a senior citizen apartment complex.