Chase City is a town in Mecklenburg County, Virginia, United States.

The Chase City High School, MacCallum More and Hudgins House Historic District, and Shadow Lawn are listed on the National Register of Historic Places.

[8] According to the United States Census Bureau, the town has a total area of 2.2 square miles (5.7 km2), all of it land.

There were 1,249 housing units at an average density of 570.0 per square mile (220.2/km2).

36.7% of all households were made up of individuals, and 21.7% had someone living alone who was 65 years of age or older.