Cheiridopsis ponderosa is a species of succulent plant from South Africa.

[1] Thick and densely papillate leaves grow in pairs.

[1] They are grey green in colour, with a rounded keel and may have minute teeth near the tip.

[1] Cheiridopsis ponderosa is endemic to the Northern Cape of South Africa.

[3] This species is considered to be of least concern by the South African National Biodiversity Institute.