ChemMedChem is a biweekly peer-reviewed scientific journal covering medicinal chemistry.

In addition to original research in the form of full papers and shorter communications, the journal contains review-type articles (reviews, minireviews, patent reviews, essays, highlights) as well as occasional book reviews and conference reports.

Topics covered include drug design, development and delivery, molecular modeling, combinatorial chemistry, drug target validation, lead generation, ADMET studies, and, as of 2017, nanomedicine (including targeted drug delivery, theranostics, and nanodrugs).

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