As currently known, it is endemic to northeastern Ecuador, but it is likely to occur also in adjacent parts of Peru and perhaps Colombia too.

[1][3] The specific name anatipes refers to the "duck-like" feet of this frog, characterized by extensive webbing between the toes.

[2] The ventral coloration is cream with large, dark brown irregular spots or blotches.

[4] Chiasmocleis anatipes occurs in lowland primary forest at elevations of 200–400 m (660–1,310 ft) above sea level.

It is found in the Yasuní National Park and the Jatun Sacha Biological Station.