Moorse was a performer in an early Chicks on Speed video (Für die Bessere Welt/ for the better world, Seppi welt ist besser/ (a member until 2006 now on Toffeetones Records).

Logan and Murray-Leslie along with co-art student Lisa Walker began working as a group at Seppi Bar to create art exhibitions and host illegal parties.

Go Records was a suicide label—the release numbers started at 10 and went down to zero; the motto was, perhaps what is wrong with the world is that things are made to grow & get bigger.

In March 2000, two Chicks on Speed LPs were released; the first, titled The Un-Releases, is not considered an official album, instead described as a "collage" of various songs in various forms.

Several EPs were issued over the next few years such as chix 52, a collection of B-52's covers and Fashion Rules that heralded the arrival of the 2003 second album 99 Cents released on Chicks on Speed records and licensed to EMI.

The album produced three more singles: "We Don't Play Guitars", a collaboration with Canadian artist Peaches, which was a hit around the world; a cover of Tom Tom Club's "Wordy Rappinghood" which saw a number of guest stars including Le Tigre; and "Flame On", a hidden track on the album with Mika Vanio.

No singles were issued from the album, though it included a new version of "Culture Vulture", a song from their previous LP release 99 Cents.

Chicks on Speed collaborated with Julian Assange, Yoko Ono, Peter Weible and Francesca Thyssen, Anat Ben David, Angie Seah, Oliver Horton and Christopher Just on the album UTOPIA released September 2014.

Chicks on Speed performed at Australian Pavilion vernisage, 55th Venice Biennale and Museum of Contemporary Art Sydney, 2013, Thyssen Bornemisza Art Contemporary 2012, Turner Prize Retrospective at the Tate in October 2007, and at MoMA in June 2006, as part of a special evening with Douglas Gordon.

Chicks on Speed's focus on fashion began in 1997 with their first stage costumes; these developed into a longtime collaboration with Kathi Glas, and more recently with Peggy Noland, Ari Fish and Jeremy Scott.

Chicks on Speed's series of what they call ObjectInstruments sees the group shy away from filling the stage with conventional band instruments, they invented their own instruments, which at times double as fashionable stage outfits –for example: Super suits, outfits which remotely trigger audio/video, and an haute couture hat which is a self-contained amplification device.

These shoes were unveiled alongside Chicks on Speed's ever-growing collection of self made ‘objektinstruments’ – A Theremin Tapestry, cigar-box synthesizers, super suits with sewn-in body sensors that trigger audio/video samples and two hats made in collaboration with Christophe Coppins and Hangar.org, based on illuminated drawings of Hildegard von Bingen, a 12th-century Christian mystic who received visions, composed ethereal airs, performed healings and even founded convents.

The DCA galleries were further transformed into a giant stage and studio set for making music videos, experimenting with no-choreography and ongoing craft projects live, including loom-weaving inspired by Bauhaus design, lectures and workshops, film screenings of their fashion archive and selected video pieces.