The Chirkuo (Russian: Чиркуо) is a river in Yakutia (Sakha Republic), Russia.

[1] In the Ust-Chirkuo Site (Yakut: Чиркуо төрдө, romanized: Çirkuo tördö) there are remains of ancient settlements by the river.

The river flows roughly northwards across the plateau along the border with Irkutsk Oblast to the west.

The last stretch and mouth area of the Chirkuo are part of the backwater of the Vilyuy Reservoir.

[5] The waters of the Chirkuo provide a habitat for the critically endangered Siberian sturgeon.