A chloride channel blocker is a type of drug which inhibits the transmission of ions (Cl−) through chloride channels.
Niflumic acid is a chloride channel blocker that has been used in experimental scientific research.
[1] Another example is anthracene-9-carboxylic acid, a potent blocker of the CLCN1-type chloride channel found in skeletal muscle, which is used to study animal models of myotonia congenita.
[2] Some antagonists of glycine receptors and GABAA receptors also act as chloride channel blockers.
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