Chlorophyllin refers to any one of a group of closely related water-soluble salts that are semi-synthetic derivatives of chlorophyll, differing in the identity of the cations associated with the anion.

Also in recent years it has been used as a home remedy to treat acne and skin conditions such as pimples or blackheads, thanks to its antimicrobial effect.

It is also available as a topical preparation, purportedly useful for both treatment and odor control of wounds, injuries, radiation burns, and other skin conditions.

In the 2020s, it again became the subject of unsubstantiated medical claims, as social media influencers promoted its use in the form of "chlorophyll water", for example.

[7] Chlorophyllin has been validated to exhibit ameliorative effects against food additive induced genotoxicity (elevating the expression of DNA repair proteins p53 and PARP) and mitochondrial dysfunction and may be used as a therapeutic tool for the management of diseases like diabetes and cancer.