Unlike other primary bone sarcomas that mainly affect children and adolescents, a chondrosarcoma can present at any age.

A small minority of secondary chondrosarcomas occur in people with Maffucci syndrome and Ollier disease.

[9] However, a definitive diagnosis depends on the identification of malignant cancer cells producing cartilage in a biopsy specimen that has been examined by a pathologist.

Earlier diagnosis is generally accidental when a patient undergoes testing for another problem and physicians discover cancer.

Chemotherapy or traditional radiotherapy are not very effective for most chondrosarcomas, although proton therapy is showing promise with local tumor control at over 80%.

Recent studies have shown that induction of apoptosis in high-grade chondrosarcoma, both directly and by enhancement of response to chemotherapy and radiation, is a valid therapeutic strategy.

Follow up scans are extremely important for chondrosarcoma to make sure there has been no recurrence or metastasis, which usually occurs in the lungs.