[2] Prior to his appointment as Parliamentary Secretary for Health in April 2014, he worked as a Consultant Paediatric Surgeon and Clinical Chairman at Mater Dei Hospital.

[3] He is a Member of Parliament for the Labour Party and was the chairman of the Foreign and European Affairs Committee at the Maltese House of Representatives.

Fearne is a founding director of the Malta Institute for Medical Education and the chairperson of Celebrities for Kids, a voluntary NGO promoting children's rights.

[6] Following the announcement of the resignation of Joseph Muscat from Prime Minister of Malta and Leader of the Labour party, Fearne was the first Member of Parliament to officially express his intention of contesting for the vacated role.

On 27 February 2019 Fearne said that abortion was the reason why Malta dropped 10 places in the Public Service Ranking of the Euro health consumer index, although the official report did not match up with this claim.

[19][20][21][22] Since 2020, Fearne has also been a member of the Global Leaders Group on Antimicrobial Resistance, co-chaired by prime ministers Sheikh Hasina and Mia Mottley.

Agreed upon in 2017, during the Maltese Presidency of the Council of the EU, the Valletta Declaration consisted of ten EU Member States: Malta, Italy, Greece, Cyprus, Romania, Spain, Portugal, Croatia, Ireland and Slovenia,[26] and aimed at establishing a technical and political cooperation on cross-border health matters such as anti-microbial resistance and price transparency of innovative medicines.

[29][30] According to Fearne, “the model that we will be proposing (...) is that member states which are [providing] funds should aim to go into agreement with the industry to share the benefits when there are new drugs on the market.

[28] While speaking at a Politico Healthcare summit in July 2019, in Amsterdam, Fearne called on his counterparts to push for new rule at European level to share drug prices among Member States.

[33] On 10 May 2024, Fearne resigned as deputy prime minister and withdrew his candidacy for the European Commission after charges were filed against him over fraud and misappropriation of funds related to an investigation into a 2015 agreement to privatize three hospitals which was subsequently annulled in 2023 by the courts.