Christian Brothers Academy (CBA) is located in the town of Colonie, New York near the Albany International Airport on a 126-acre (0.51 km2) campus built in 1998.

In 1854, the Christian Brothers were invited to Albany by Bishop John McCloskey, to open an orphan asylum for boys.

To help support the asylum, the Brothers began a pay school in 1859 in which eighty boys enrolled.

Through the interest of influential friends and alumni, city and county officials in 1937 made available to the Brothers a plot of land.

Bishop Edmund Gibbons and Mayor John Boyd Thatcher II urged all citizens of Albany to contribute.

In 2012, the school's administration and the board of trustees made the decision to become a Junior Reserve Officers' Training Corps (JROTC) optional institution.

Multiple science labs, a technology center, as well as a lecture hall equipped with all the latest media tools, became available to faculty and students.

The wing added a new professionally designed music room, a new STEM lab, and four additional classrooms to accommodate the school's growing enrollment.

The school now offers over 86,000 square feet of instructional and administrative spaces, and over 30 acres of dedicated athletic facilities.

The high school program allows students to take honors level courses in all of the core disciplines (mathematics, science, social studies, English and foreign language) through a combination of Advanced Placement (AP) offerings and regularly scheduled courses.

The College Board offers the AP program to high schools as an opportunity for students to pursue advanced credit in specific disciplines.

The school offers AP courses in Spanish V (also College in High School/"CHS"), statistics, calculus, biology, physics, chemistry, US history, world history, English literature and composition, English language and composition, and computer science.

CBA's athletics program is classified by Section II as a "Class AA" school, the highest classification in New York State.