[1][2] After attending Liceo classico in Rome, where he had Carlo Verdone as his deskmate,[3] De Sica worked in a hotel in Venezuela, where he began his career as an artist.

De Sica developed his own style of comedy and entertainment also in Rai television shows, such as Bambole, non c'è una lira, which gave him a large success in 1978.

With his father's help, he was able to take his first steps in the movie world with such teachers and mentors as Roberto Rossellini (Blaise Pascal, 1971), Vittorio De Sica himself (A Brief Vacation, 1973), Pupi Avati (House of Pleasure for Women, 1976) and Salvatore Samperi (1979 Liquirizia and 1981 Chaste and Pure).

[4] After Night club, the last film directed by Italian director Sergio Corbucci, Christian De Sica became one of the most famous interpreters of the "cine-panettone" (comedies that reach movie theatres during the Christmas season) and formed till 2005 a partnership with actor Massimo Boldi.

These films, done in burlesque style, tend to be well received at the box office, if not by critics, at times even outstripping better known and expensively made movies such as the Harry Potter series.