Christian Louis I (1 December 1623 in Schwerin – 21 June 1692 in The Hague) was a reigning duke of Mecklenburg-Schwerin.

However, he was never appointed, because when Administrator Ulrik III died on 12 August 1633, the Bishopric fell to Wallenstein as a completed fief.

His first wife was Christine Margarethe of Mecklenburg-Güstrow (31 March 1615 – 16 August 1666), the second daughter of Duke John Albert II.

However, on 16 October 1660, a divorce was pronounced by an ecclesiastical court composed specifically for this case by Christian.

It was, however, declared valid by a committee of ten professors of canon law of the University of Paris the Sorbonne.

The exact date of Elisabeth Angelique's wedding to Christian Louis is not known with certainty, but it was probably on 3 March 1664.