Christina Messineo Annunziata is an American medical oncologist researching molecular signal transduction in ovarian cancer.

She is an investigator in the National Cancer Institute's women's malignancies branch and head of the translational genomics section.

Annunziata joined the NCI laboratory of Louis M. Staudt in the metabolism branch to investigate NF-kappaB signaling in multiple myeloma.

She returned to the medical oncology branch to extend her study of these molecular pathways in the ovarian cancer model.

Annunziata holds board certification for the practice of medical oncology.