Species within Chromodoris are commonly found in tropical and subtropical waters, living as members of reef communities and preying primarily on sponges.

[2] A molecular phylogeny of the family Chromodorididae resulted in this genus being restricted to a smaller number of species than formerly, most of which have longitudinal black lines on the mantle.

Chromodorids breathe oxygen principally through their gills, usually positioned in a featherlike structure located around the anus at their posterior, called the branchial plume.

These MDFs have been shown to harbor extremely high concentrations of distasteful and potent compounds in comparison to the rest of their body.

From here, the female lays eggs into a substrate, which hatch planktonic vestigial veliger larva, who will further evolve into adults.