The Church of St. John Nepomucene is a Roman Catholic parish located on East 66th Street and 1st Avenue in Manhattan, New York City.

[2] The founders of the church were recent immigrants from Slovakia, who began meeting in St. Brigid's Parish at 8th Street and Avenue B in about 1891 and established the Society of St. Matthew to organize their own parish.

[4] The church, school and rectory were built for $300,000.

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