After the fire in 1737, from 1738 to 1748, architect Johann Christoph Glaubitz completely reconstructed the church in style of late Baroque.

During the 1827-28 reconstruction, architect Karol Podczaszyński destroyed the bulk of the sumptuous Baroque interior - nearly 3000 carts with splinters of altars, sculptures and stucco works were taken to a dump; chapels suffered the least.

During Hitler's occupation, the Reverend Alfonsas Lipniūnas, who was later imprisoned by the Nazis in the Stutthof camp and perished, delivered rebellious sermons in the church.

The tower, consisting of 5 gradually decreasing portions, is the tallest building of Vilnius Old Town (69 metres (226 ft)).

The altars are positioned in a semi-circle, on varying planes and levels, and light illuminates them through the Gothic presbytery windows.