Her research is focused in chromatin regulation and how changes in cellular structure can lead to human diseases, such as Cancer, Neurodevelopmental disorders, and others.
She moved to Stanford University as a graduate student, where she specialized in cancer biology under the supervision of developmental biologist Gerald Crabtree.
After completing her doctorate at Stanford University she transitioned directly to faculty at Dana–Farber Cancer Institute and Harvard Medical School.
[2] In 2014, at the age of 28, Kadoch established her independent laboratory at the Dana–Farber Cancer Institute and Harvard Medical School, as an Assistant Professor.
[7] The fusion oncoprotein subunit, SS18-SSX, appears to break the guidance system of SWI/SNF (BAF), targeting it aberrantly on chromatin and activating genes that support cancer development.