Cipocereus crassisepalus is a species of cactus endemic to the state of Minas Gerais in Brazil.

Cipocereus crassisepalus grows tree-shaped, branches irregularly and reaches heights of up to 2 meters.

[2] Cipocereus crassisepalus is widespread in the Brazilian state of Minas Gerais in the Diamantina region.

[3] The specific epithet crassisepalus is derived from the Latin words crassus for 'thick' and sepalum for 'sepal' and refers to the thick-fleshed outer perianth segments.

Nigel Paul Taylor and Daniela Cristina Zappi (* 1965) placed the species in the genus Cipocereus in 1991.