It has been found in warm tropical waters with low seasonal changes, ranging from 26°N to 25°S, where it occupies a distinct ecological niche compared to other placozoan lineages.

[4] Sexual reproduction has been reported to occur in the placozoan clade identified with strain H8,[5][6] which was later found to belong to genus Cladtertia.

[7] The sharing of alleles between heterozygous and homozygous individuals was also observed, a phenomenon resulting from the combination of gametes during sexual reproduction.

Haplotype H6 was confirmed as a distinct species, although it was left undescribed due to a lack of material from which to designate a type specimen.

[13] In a 2024 study, H6 was found to occupy a basal position in the genus compared to C. collaboinventa and H8, with the latter two sharing an inversion of the tRNA-Thr and tRNA-Lys region as a structural synapomorphy.

[14] Compared to other placozoan lineages, Cladtertia is only known from a restricted range of latitudes, from 26°N to 25°S, and has been sampled in the Pacific, Atlantic and Indian Oceans.