Claire Temple first appeared in Luke Cage, Hero for Hire #2 and was created by Archie Goodwin and George Tuska.

[13] Cage is finally exonerated for the crime that originally put him in prison, but in the retitled Power Man and Iron Fist #50 (April 1978), Claire can no longer handle him constantly being in danger, and they separate.

[17] Soon after, he decides to quit fighting crime because the local citizens seem ungrateful and derisive, but she convinces him how important his work is.

[21] As part of the All-New, All-Different Marvel, Claire is a doctor who specializes in dealing with super-powered humans and bionic implants.

[volume & issue needed] After Rage had been arrested upon being accused of a pawn shop robbery done by Speed Demon and Man Mountain Marko and is then beaten up in the penitentiary's Z Block by the super-powered prisoners which he previously apprehended, he was taken to the hospital where Sam is told by Claire Temple that Rage will not survive due to the extensive brain damage he sustained.

[24] During the Secret Empire storyline, Claire Temple was in a Darkforce-covered Manhattan trying to tend to the ill civilians, as she tells the Defenders that the hospital has limited medical supplies.