Clarksville is a hamlet in the town of New Scotland, Albany County, New York, United States.

It is situated along Delaware Turnpike (New York State Route 443) in the southern part of the town at the foot of the Helderberg Escarpment.

The post office and hamlet were later named Clarksville for Adam A. Clark, who came to the area in 1822.

[3][4][5] Clarksville is situated in the southern portion of the town of New Scotland, along Delaware Turnpike (New York State Route 443) east of and at the foot of the Helderberg Escarpment.

The hill is part of a wilderness preserve owned by the Mohawk Hudson Land Conservancy.