Selkirk is a hamlet in the town of Bethlehem, Albany County, New York, United States.

A major freight railyard operated by the Selkirk Subdivision of CSX Transportation[1] is located there; all of the CSX freight traffic going to or from Boston goes through Selkirk on its way to points north, south or west.

The route is also used by traffic from New York City via the Alfred H. Smith Memorial Bridge to points west, a detour known as the Selkirk hurdle.

Also in Selkirk is Audubon International, a non-profit environmental educational organization.

137, and Schoonmaker House are listed on the National Register of Historic Places.