Further work included television guest appearances on Falcon Crest; Riptide; Hunter; Quantum Leap; Matlock; Murder, She Wrote; L.A. Law; and It's Garry Shandling's Show; and as a series regular on Berrenger's.

[17] Christian's film career launched with Clean and Sober opposite Morgan Freeman and Michael Keaton, Never on Tuesday with Andrew Lauer and Peter Berg,[18] The Hidden with Kyle MacLachlan, 20th Century Fox's The Chase with Charlie Sheen, the Columbia comedy Hexed, and Adam Rifkin's The Dark Backward.

Series creator J. Michael Straczynski maintains that she chose to leave of her own accord,[20] while Christian stated that she wished to return for the final season but was released when she requested a reduction in the number of episodes in which she would appear so she could complete another project.

[27] In 2004, she returned to Laguna Beach, California, where she attended high school, to star in the American premiere of Michael Weller's play What the Night Is For with Kip Gilman and directed by Richard Stein.

In addition, Christian played Janine Foster in the Doctor Who audio drama The Reaping[29] and appeared in the films The Garden with Lance Henriksen[30] and Half Past Dead with Steven Seagal.

She also plays the title role in the Anne Manx radio series[32] and voices characters in major video games including Call of Duty: Infinite Warfare,[33] The Elder Scrolls V: Skyrim, Fallout 4, and Pizza Morgana.

[46] To increase awareness of this treatment, she collaborated with Morgan Grant Buchanan to write a book, Babylon Confidential,[36] and made a documentary, One Little Pill, about the science behind this method.