The hospital was officially inaugurated on December 3, 2015 by then Crown Prince of Abu Dhabi and Deputy Supreme Commander of the Armed Forces Sheikh Mohammed bin Zayed Al Nahyan.

The hospital was initially scheduled to begin full-service operations to patients by the fourth quarter of 2013.

[2] Construction was delayed for another 18 months prior to opening its facility to the public in May 2015 due to logistic challenges faced by the massive size of the project.

Having 340 doctors and 2,918 nurses and other workers, the hospital currently has more than 50 medical and surgical specialities and is designed to operate five different specialist centres of excellence covering digestive disease, eye, heart and vascular disorders, neurological treatment, and respiratory and critical care.

Eighty percent of the successful applicants are US-trained, and the rest were trained in western Europe.