Clifton Randolph Pennington (born June 15, 1984) is an American former professional baseball infielder who played in Major League Baseball (MLB) for the Oakland Athletics, Arizona Diamondbacks, Toronto Blue Jays, Los Angeles Angels, and Cincinnati Reds between 2008 and 2018.

On August 12, 2008, he was called up from the Triple-A Sacramento River Cats, and made his Major League debut that day against the Tampa Bay Rays going 0-for-3 in a 2–1 win for the Athletics.

Later that day, Pennington was diagnosed with Bell's palsy, which paralyzes one side of the face and prevents him from controlling his muscles.

[9] On April 13, 2013, Pennington was ejected for the first time in his MLB career for arguing a correctly ruled strike three call made by umpire Jim Reynolds.

[10] In an 18 inning game on 24–25 August 2013 at the Philadelphia Phillies, Pennington walked five times, one shy of the Major League record.

[14] On August 8, 2015, Pennington was traded to the Toronto Blue Jays along with cash considerations for minor league shortstop Dawel Lugo.

[22] On February 15, 2019, Pennington signed a minor league contract with the Oakland Athletics that included an invite to Spring Training.

Pennigton was one of 28 Athletics selected to go to Tokyo to play two regular season games against the Seattle Mariners.

[24] Following the 2021 season, Pennington joined the coaching staff of the Dallas Baptist Patriots as recruiting coordinator.