Prior to playing professionally, Brown attended Plant High School and then Oklahoma State University.

[1][2] Brown played his final season with Oklahoma State in 2007, hitting .335 with 22 home runs, 71 RBI and 23 stolen bases.

He split 2010 between the RockHounds and Sacramento River Cats, hitting a combined .283 with 15 home runs, 69 RBI and 22 stolen bases.

On December 16, 2010 Brown, with pitcher Henry Rodriguez were traded to the Washington Nationals in exchange for Josh Willingham.

[3] Brown made his major league debut for the Washington Nationals on September 6, 2011, appearing in three games during the season, pinch-hitting three times, without getting on base.

On August 16, the Red Sox designated Brown for assignment, after he appeared in three games at the big league level with the club.