[1] The freezing point depression osmometer is also used in various medical practices, including pharmaceutical manufacturing, quality control laboratories, and clinical chemistry.

The use of osmometers began in the late nineteenth century after Van't Hoff won a Nobel Prize for his research and discovery that the relationship between the osmotic pressure of dilute colloid solutions and concentration was consistent with the ideal gas law.

[5][6] The study established its advantages over other conventional concentration osmometers which rely on the osmotic pressure profile and it was found to be ideal for dilute, biological samples.

As compared to the other methods, the freezing point depression osmometer has a high level of precision and accuracy, making its application in clinical practices safe.

Osmometry is widely used in pharmaceuticals, quality control laboratories, and clinical chemistry to measure the osmolality in aqueous solutions accurately.

It is commonly used in medical clinics to assist with various pharmaceutical practices,[10] including the development of lens care solutions and eye drops.