[2][3] Diseases associated with this family include: yellowing and necrosis, particularly affecting the phloem.

[3][4] Genome type and transmission vector are two of the most important traits used for classification.

Ampeloviruses and Closteroviruses have monopartite genomes and are transmitted by pseudococcid mealybugs (and soft scale insects) and aphids respectively.

[3] Genera:[2] Unassigned species:[2] Viruses in the family Closteroviridae are non-enveloped, with flexuous and filamentous geometries.

The virus exits the host cell by tubule-guided viral movement.