San Luis' main rival is fellow platense club La Plata.

A year later "Club San Luis" was founded and started playing friendly games, being Horacio Lascano its provisory president.

In 1967 the team debuted in "Tercera de Clasificación" (then the third division of Argentine rugby) championship, being the runner-up at the end of the season.

In 1998 the team got its only title to date, the Nacional de Clubes championship, shared with San Cirano after a [draw in the final game.

In 2000 San Luis toured over South Africa for the first time The women's field hockey section was added in 2007, and its stadium opened a year later.