[2][3] The series was created by Raven Metzner and stars Sterling Beaumon as Seamus, Sarah Desjardins as Whitney, Kendall Amyre Ferguson as Agnes, Ana Golja as Liz, Stephan James as Dmitri, and Zach Mills as Lucas.

The series follows six very different young sleuths nicknamed after the characters from the game of the same American name as they witness a terrible crime and embark on a mysterious adventure they could never have imagined.

Along the way, they find they have more in common than they thought, as they uncover hidden treasures and decipher cryptic knowledge to reveal a dark and secret society.

[7] Brian Lowry of Variety said "Marketing-driven constructs are often the kiss of death creatively speaking, however, the commercial template surrounding Hub's miniseries based on "Clue"—consisting of five half-hour segments—is clever enough to overcome such concerns."

Lowry continued, "In short, Hub is replicating some of the old razzle-dazzle of local kids' TV, for better or worse, around a production that ought to possess some multigenerational appeal.