He played in Major League Baseball (MLB) for the St. Louis Cardinals, Toronto Blue Jays, Houston Astros, Tampa Bay Rays and Baltimore Orioles.

Phenix City won the United States championship game,[1] before losing in the finals to Osaka, Japan, 5–0.

[citation needed] For the 2007 season, Rasmus was assigned to the Springfield Cardinals of the Class AA Texas League.

[13] He earned his first major league hit in his second career at-bat, on a single to right field off Pittsburgh's Ian Snell.

[14] On June 19, he had his first four-hit game, in a 10–5 victory against the Kansas City Royals in which Pujols scored his 1000th career run.

[citation needed] Rasmus hit his first career grand slam against the Cincinnati Reds' Bronson Arroyo.

[17] Rasmus finished his second full season with St. Louis with 23 home runs, 66 RBIs, and a .276 batting average in 144 games.

[15] On July 27, 2011, Rasmus was traded to the Toronto Blue Jays along with P. J. Walters, Brian Tallet, and Trever Miller for Edwin Jackson, Octavio Dotel, Marc Rzepczynski, and Corey Patterson.

[18][19] As a Blue Jay, Rasmus finished the season with a .173/.201/.316 triple-slash line along with three home runs and 13 RBIs in 35 games.

In an interleague game against the Milwaukee Brewers on June 19, Rasmus hit the first of three straight solo home runs by the Blue Jays, followed by José Bautista and Edwin Encarnación, the first time in the 2012 season that the Jays went back-to-back-to-back with home runs, and the sixth time in franchise history.

On January 14, 2013, Rasmus signed a one-year contract worth $4.675 million with the Blue Jays, avoiding salary arbitration.

On July 28, 2013, Rasmus hit a walk-off single against the Houston Astros, leading the Blue Jays to a 2–1 victory.

Later that day, he was the subject of an article naming him, along with Adam Jones and Mike Trout, as the best active center fielders in baseball.

[24] On August 2, 2013, Rasmus was named the Blue Jays Player of the Month for July by the Toronto chapter of the Baseball Writers' Association of America.

[28] Rasmus was hit in the face by a ball thrown by Anthony Gose during warmups prior to the bottom of the first inning in a game against Boston on September 20.

[33] Rasmus experienced a decline in his play from that point onward, and, beginning in late August, was demoted to a bench role in favor of Gose, Kevin Pillar, and later Dalton Pompey.

He received only one start in September and had a total of 13 at-bats, finishing the season batting .225/.287/.448, with 18 home runs and 40 RBIs in 104 games.

Eligible for free agency for the first time in his career, it was widely speculated that Rasmus would not seek to re-sign with the Blue Jays, nor would Toronto be interested in retaining him.

[35] As an everyday starter for the Astros, he finished the 2015 season batting .238/.314/.475 with 25 home runs and 61 RBIs in 137 games played.

In the process, he set an MLB record for having an extra-base hit in each of his first six career postseason games, dating back to his tenure with the Cardinals.

[36] On November 12, 2015, Rasmus became the first player in MLB history to accept a qualifying offer, signing a one-year, $15.8 million contract to return to Houston.

[59] He was activated on June 21 and returned to the starting lineup that night as Baltimore faced Max Scherzer and the Washington Nationals.