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Coleocephalocereus is a genus of erect and semi-erect columnar cacti from Brazil.

These species develop a cephalium with wool and bristles.

They are common to the inselbergs of the Brazilian Atlantic rainforest, and can comprise a dominant portion of the flora in these isolated, dome-shaped rocky outcrops.

[2] As of September 2023[update], Plants of the World Online accepted the following species:[1]