It is on the Edgware branch of the Northern line, between Burnt Oak and Hendon Central stations, and is in Travelcard Zone 4.

The platforms were located underneath the east–west road, not just on one side, and the station had a classical style building designed by Underground Architect Stanley Heaps.

[7][22] The new station building would replace the 1960s ticket hall, albeit located over the tracks rather than built to the side, as at present.

[21] In February 2024, it was announced that the station would close temporarily from Friday 7 June 2024 until December 2024 to allow construction work to take place.

[23][24] The station reopened in December 2024 after completion of phase 1 – the staircase was reconstructed but the new entrance remains incomplete.

The Colindale tube station was also a popular destination for travellers intending to reach the shopping centre of Oriental City up until its closure.