Both compilations collect all the early singles and the entire Earth A.D./Wolfs Blood album, and are meant to complement Walk Among Us (not represented because Warner Bros. owns the rights) and Legacy of Brutality with little overlap.

They were recorded in 1986, several years after the Misfits broke up, by Glenn Danzig and Samhain bassist Eerie Von for a sequel to Walk Among Us.

The four Walk Among Us-era tracks ("Hate Breeders", "Braineaters", "Nike-A-Go-Go", and "Devil's Whorehouse") included on Collection II were also recorded during the same sessions, and featured no participation by any other Misfits.

This mix, exclusive to this compilation and not included on the box set, is characterized by its use of reverb and more prominent guitar.

"Return of the Fly" is a song recorded at the same time as the above three during the Static Age sessions, but had previously only been available via bootlegs.

It was originally conceived as the second part of a medley with "Teenagers From Mars," and was mixed together with that song for the Horror Business EP.