[2]: 6 The church building is listed on the National Inventory of the Cultural Property of the Maltese Islands.

[4] The church hosts fine artistic works, including the magnificent altarpiece by Matteo Perez d'Aleccio, the paintings by Attilio Palombi, and Giuseppe Calì.

[2]: 8, 15, 35  The wooden titular statue of St Paul was carved in 1659 by Melchiorre Cafà, the brother of Lorenzo Gafà who designed the dome.

[2]: 42, 18  The statue is paraded through the streets of Valletta on the feast day of St Paul's Shipwreck, February 10.

[1][5] One can also view the relic of the right wrist-bone of St Paul, and part of the column from San Paolo alle Tre Fontane, on which the saint was beheaded in Rome.