This settlement was established by the last Spanish governor of Salta, Nicolás Severo de Isasmendi, in 1831.

His daughter Ascención imported grapevines from France and planted them in the area at an average altitude of 2200 m, which is extremely high for viticulture.

Under these conditions, growing grapes is a challenge, but it has the advantage that insects, pests and diseases are less common.

Swiss vigneron Donald M. Hess bought the Bodega Colomé and vineyards in the neighbourhood in 2001.

[2] In addition, Donald M. Hess has built a museum in Colomé dedicated to the American artist James Turrell, which opened in 2009.