In 2006, 25,000 pesos was robbed from a secondary school cooperative after a shootout with police in the streets of the colonia as the robbers tried to escape.

[5] In 2008, the third highest ranking police official in Mexico City, Hugo Moneda Range, was shot to death on the intersection of Calzada de los Misterios and Berlioz.

[9] An abandoned green area near where Paseo de la Reforma, Calzada Misterios and Eje 2 Norte converge was cleaned up and rehabilitated to become the site of a 3.8-meter tall statue of the wrestler El Santo, by sculptor Edwin Barrera.

It was placed here because the wrestler lived near here on Belisario Dominguez Street with his siblings to fight in the nearby Arena Coliseo in the city center.

[2] This colonia, along with neighboring Tepito, Lagunilla and Tlatelolco were areas mostly inhabited by indigenous and mestizos, both poor, as well as large haciendas and monasteries during the colonial period.

One writer, Gonzalo Peredo Goméz states that the name comes from a passage in the work Don Quixote, but spelled "Perabillo," which referred to a place in La Mancha.

[2] In 2000, residents of the colonia burned in effigy the three presidential candidates (Vicente Fox, Cuauhtémoc Cárdenas and Francisco Labastida) on Wagner Plaza.

[11] Started in the mid-2000s, the La Casa de Todos association operates a pizzeria and bakery that employs street children.